The Elata Foundation - Advancing the science of Transcranial Magnetic Stimulation (TMS)

Current Studies - North America

New US study: Postpartum Depression at Washington University in St. Louis

New Australlian studies: Treatment Trials for Schizophrenia, schizoaffective disorder and depression

Magnetic Brain Stimulation for the Treatment of Postpartum Depression

This study will evaluate the safety and effectiveness of magnetic brain stimulation for the treatment of postpartum depression.

Ages Eligible for Study	21 and older who are Postpartum at least 30 days or up to one year
Genders Eligible for Study	Female Only
Inclusion Criteria	· Postpartum Depression · Edinburgh depression scale points over 9 · Available for a one hour visit Mon-Friday (9am to 4PM daily for 4 weeks) English Speaking
Exclusion Criteria	· Current use of antidepressants · Diagnosis of postpartum psychosis · Current substance abuse · Seizures or history of head trauma

Principal Investigator	Contact Name	Location	Phone Number	Physical Address	Email Address
Garcia, M.D	Patricia Flynn BSN, R.N	Missouri, USA	314-362-1839	Washington University, St. Louis, Missouri	flynnp@psychiatry.wustl.edu

Principal Investigator: Keith Garcia, M.D.

Sub-Investigator coordinator: Patricia Flynn BSN, R.N. - 314-362-1839 or flynnp@psychiatry.wustl.edu

Magnetic Brain Stimulation for the Treatment of Adult Depression

This study will evaluate the safety and effectiveness of magnetic brain stimulation for the treatment of major depression in depressed adults with moderate treatment resistance.

Ages Eligible for Study	21 Years - 70 Years
Genders Eligible for Study	Both
Inclusion Criteria	· Diagnosis of major depression with a current episode · Hamilton Rating Scale for Depression score higher than 20 · No response or intolerance to antidepressant medication in the current depressive episode
Exclusion Criteria	· Current use of antidepressants · Diagnosis of psychosis or anxiety disorder · Current substance abuse · Seizures or history of head trauma

Principal Investigator	Contact Name	Location	Phone Number	Physical Address	Email Address
William McDonald, MD	Sinead Quinn	Georgia, USA	404-728-6957	Emory University, Atlanta, Georgia	squinn@emory.edu
Sarah H. Lisanby, MD	Seth Disner	New York, USA	212-543-5767	Columbia University, New York	disners@pi.cpmc.columbia.edu
Mark S. George, MD	Samet Kose, MD Berry Anderson, RN	South Carolina, USA	843-876-5142	Medical University of South Carolina, Charleston	kose@musc.edu andersob@musc.edu
David Avery, MD	Chandra Wajdik	Washington, USA	206-731-2436	University of Washington, Seattle	cwajdik@u.washington.edu

Study chairs or principal investigators:
Mark S. George, MD, Principal Investigator, Medical University of South Carolina

Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception

The purpose of this study is to investigate the effects of transcranial magnetic stimulation on pain perception.

Ages Eligible for Study	21 Years - 75 Years
Genders Eligible for Study	Both
Inclusion Criteria For Health Adults	· Between age of 21 and 75 No prescription medications in previous 3 months No seizure history No depression Not suicidal No anxiety No hospitalizations or surgeries in previous 6 months No history of chronic pain conditions No implanted metal devices (e.g., pacemakers, metal plates, wires) Not pregnant No alcohol abuse/dependence history in previous 6 months No illicit drug use in previous 6 months Capable of reading, writing, giving consent, following instructions No history of brain surgery or history of loss of consciousness >15 minutes No history of autoimmune or endocrine disorder No significant anxiety about entering MRI scanner
For Patients with TGN	Between age of 21 and 75 No seizure history Not taking medications shown to increase seizure risk (6 months) Not suicidal No hospitalizations or surgeries in previous 3 months No implanted metal devices (e.g., pacemakers, metal plates, wires) Not pregnant No alcohol abuse/dependence history in previous 6 months No illicit drug use in previous 6 months Capable of reading, writing, giving consent, following instructions Chronic TGN (>6 months), not significantly relieved by pharmacological treatment -Paroxysmal attacks of facial or frontal pain lasting a few seconds to less than 2 minutes -Pain has at least 4 of the following characteristics: 1) distribution along 1 or more divisions of the trigeminal nerve, 2) Sudden, intense, sharp, superficial, stabbing, or burning quality, 3) severe pain intensity, 4) precipitated by trigger areas or certain daily activities (e.g., eating, talking, washing face, cleaning teeth), 5) no symptoms between paroxysms, 6) pain is unilateral -No neurological or sensory deficit is present -Attacks are stereotyped in the individual patient -Other cause of facial pain are excluded by history, physical examination and special investigation No significant anxiety about entering MRI scanner

Principal Investigator	Contact Name	Location	Phone Number	Physical Address	Email Address
Jeffrey J. Borckardt, Ph.D.	Jeffrey J. Borckardt, Ph.D.	South Carolina, USA	843-876-5142	Medical University of South Carolina, Charleston	borckard@musc.edu

Study chairs or principal investigators:
Jeffrey J. Borckardt, Ph.D., Principal Investigator, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina
Mark S. George, M.D., Medical University of South Carolina, Mentor
John G. Arena, Ph.D., Medical College GA, Co-Mentor
Mark P. Jensen, Ph.D., University of Washington, Co-Mentor
David Patterson, Ph.D., University of Washington, Co-Mentor
Scott T. Reeves, M.D., Medical University of South Carolina, Co-Mentor
A. Richard Smith, M.D., Medical University of South Carolina, Co-Mentor
Joseph G. Reves, M.D., Medical University of South Carolina, Co-Mentor
Sunil Patel, M.D., Medical University of South Carolina, Consultant
Susan Middaugh, Ph.D., Medical University of South Carolina, Consultant